Target Identification and Validation
Target Identification and Validation is a critical phase in the drug discovery process that focuses on recognizing and confirming biological molecules—such as proteins, genes, or pathways—that are directly involved in disease progression. This session explores both experimental and computational strategies for identifying potential drug targets and validating their relevance and drug ability. Topics include genomics and proteomics approaches, CRISPR-based validation, RNA interference, bioinformatics tools, and disease pathway analysis. Emphasis is placed on ensuring that selected targets are not only biologically significant but also therapeutically actionable, thereby reducing the risk of failure in later drug development stages.
• Computational approaches for target prediction
• Network-based drug-target interaction studies
• Drug repurposing and repositioning strategies
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